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The girls are back for the fourth installment of Residential Evil Chaos Streets. In this episode, Clair and Jill are making their way to the lab while Ana heads to the other side of town to do some research. They need to find out how to stop MutantXXX infections. Confronted by mutant dogs, they get bit and need to take quick measures to prevent the virus from turning them into sex craving bitches for the dogs. The two finally let their feeling show with a girl on girl scene in the streets.
They are not safe for long, however, as Hornballs track them down and impregnate the two girls with slimy tentacles and egg sacks that the girls must push out of their full bellies before its too late.
They have infected again, perhaps round two of pussy licking in in-store? Not so fast, two Lickers interrupt them and use their massive alien cocks to fill up the now sex starving girls, with Ana so far away who will save them this time?